I'm not sure I remeber what it was like to win in PLO but looking at my PTO database, big pairs have made me a lot of money, I have been lucky to flop set over set vs some donkeys that dont understand that bottom set is crap in PLO. Big wraps have also been a nice moneymake for me. I'm actually havent won a big pot with AAxx yet in almost 10k hands.

I guess a better question is what situation do you make the majority of your money in?

For example in HE I make most of my money against player who
- Thought their TPTK was good
- Thought their over pair was good.

In PLO8 I make a lot of money against
- People who call pot sized bets with nut low draw / nut low
- Players who think their bad two way hands makes a good overall hand

What at the situations that make the most money in PLO?
- Set over set?
- A high flush vs. K High flush?
- ...

I really like your way of formuating that, Goop!

The ones you mention are definitely biggies. In practice, I run into fewer set over set situations, though, than flush over flush.

Here's another one, that I can't quite formulate as cleanly: Superior hands on paired boards. Basically, better full houses or quads against inferior full houses or trips.

Finally, I think this is the most important one of all, although it probably sounds a little vague: Having both a made hand AND redraws in contest situations.

Basically, let's say you bet and get a pot-sized raise. The raise can actually mean several things--mainly, either they have something like flush draw or wrap or else a made hand better than yours. Like, on a board of 76Q with two spades, and you have 6789 with two spades. Ok, if they have QQ, you're behind, but you take away boating outs, the 5 and the T are clean for you, and you probably have the flush outs, although not for sure.

But, if they have the raw flush draw, you take away THEIR outs with your spades, AND you have a made hand so that they're the one who needs to catch up.

Anyhow, with 6789 and low flush draw, I think you're stronger (I'll go all the way with that one on the given board for sure) than with something even like 89TJ, which is also VERY rough to lay down on that board (honestly, I'm not sure I can do that either). But on the 89TJ, you do have to catch up for sure, since you currently have nothing. Their A-high is probably (just guessing, it probably depends somewhat on how many spades are in your 89TJ) currently ahead if they have the A-high spade draw alone, and certainly if they have the spade draw with a Q pair, an overpair or even JJ or TT.