Before he folded, he asked if I had a set of 4's and folded J2. Does this play work on majority of the players?
PokerStars No-Limit Hold'em, $0.25 BB (8 handed) from (Format: FlopTurnRiver)

BB ($12.15)
UTG ($8)
UTG+1 ($25.05)
Hero ($22.35)
MP2 ($25)
CO ($35.15)
Button ($33.90)
SB ($12.45)

Preflop: Hero is MP1 with 4, 4.
2 folds, Hero calls $0.25, 1 fold, CO calls $0.25, 2 folds, BB checks.

Flop: ($0.85) 8, J, 2 (3 players)
BB checks, Hero checks, CO checks.

Turn: ($0.85) 4 (3 players)
BB checks, Hero bets $0.75, CO raises to $1.5, BB folds, Hero raises to $4.5, CO folds.

Final Pot: $6.85

Results in white below:
No showdown. Hero wins $6.85.

well he open called j2 from the CO, checked behind on a straight and flush draw board and minraised the turn with another draw added. I think he had nothing. And most people at 25nl will not fold 2pr there so I don't recommend that bluffing line if you want 2pr to fold.