King high flush for a full stack? Hell yeah. Every time. Unless it's a 4-flush board in which case my 1-card 2nd nuts is a lot less exciting. In those cases it depends on how the hand played out.
100 BBs is not that much to win or lose in a hand. If you feel like it is, you're playing at a level too high for your bankroll -- which is another issue entirely.
Here's a hand where I was glad to have had a full stack.
$50 NL at Bodog. I get
[5d] in the BB. All fold to the SB who completes. I raise to $2 because I'm going to raise pretty much every time someone completes hu in the SB. He instacalls.
Flop pot $4. Axx with two diamonds. He bets $2, I raise to $7, he calls.
Turn pot $18 brings my flush. He checks, I bet $15, he calls.
River pot $48 is a blank. He checks, I push (less than pot obviously), he calls and flips AT no diamonds.
It doesn't even matter that I had the flush. What matters is that this guy was willing to stack off for a full stack with top pair lousy kicker on a 3-flush board -- when I had shown strength literally on every street. And this happens all the time: a lot of players are calling stations and love to call you down. (Especially in blind battles.)
If I had had only $30 behind, I would have left $20 in profit on the table. Even when you're running really well, it's tough to make much more than $20 per hour at $50 NL (playing 3 tables, the max at Bodog). So by playing short-stacked I would have left an hour's worth of profit on the table in just one hand. Not good.