I went to the following debate in my little head and dont find any clear answer, or really simple solution
I go often to the crucial choice when I have the nuts on the river to gain the maximum against my opponent.
do u think it is preferable to bet pot with the nuts, half pot, 1/3 pot etc....
briefly what are your plans with that and how consequeltly do you manage your bets on the river when you are not sure to hold the nuts against a solid opponent who could play back at you...

A lot of it depends on what you had your opponent on on the turn, what hit on the river, how big are the 2 stack sizes, how big is the pot, who has position, what do you know about your opponent, and what does your opponent think of you?

If your opponent is bad, and the board was paired on the turn, you have to assume they have a smaller full house. If that is the case you can probably get in a big bet.

If the board had 3 spades on the turn and you had a set and hit a full house on the river, they prolly had the flush and are scared of the board pairing. Now you're gonna have to throw out a small bet.

What size do you play? I really doubt you're gonna find any good players "playing back at you" on the river with nothing. If they are raising you theres a 98% chance they just have a huge hand. There are very few people under $400 PLO that are gonna be tricky enough for that.

Are you or your opponents very shallow now? Then your decision is easy, bet it all.